Description

(2R,3R,4R)-4-Hydroxyisoleucine is a non-proteinogenic amino acid derivative with a specific stereochemical configuration. This compound is valued for its role as a key bioactive ingredient and a critical chiral building block in advanced synthesis. It is primarily sought after by manufacturers in the pharmaceutical, nutraceutical, and high-purity chemical synthesis sectors for research and production purposes.

Application

• Pharmaceutical Intermediates: Serves as a crucial chiral synthon for the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Nutraceutical & Dietary Supplements: Used as a bioactive component in formulations targeting metabolic health, due to its studied properties.
• Biochemical Research: Employed as a standard or reagent in metabolic pathway studies, enzymology, and pharmacological research.
• Cosmeceuticals: Incorporated into advanced skincare formulations for its potential bioactive benefits.
• Asymmetric Synthesis: Utilized as a starting material or catalyst in stereoselective chemical reactions to produce enantiomerically pure compounds.

Basic Information

Product Name	(2R,3R,4R)-4-Hydroxyisoleucine
CAS No.	60010-78-8
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	(2R,3R,4R)-2-Amino-3-methyl-4-hydroxypentanoic Acid; 4-Hydroxy-L-isoleucine; (4R)-4-Hydroxy-L-isoleucine; L-4-Hydroxyisoleucine; (2S,3R,4S)-4-Hydroxyisoleucine (enantiomer); HIL; 4-OH-Ile
EINECS	Contact for details

Quality Control

Our (2R,3R,4R)-4-Hydroxyisoleucine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for pharmaceutical and research applications. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.