Description

Hydroxyproline is a non-essential amino acid derivative, a key structural component of collagen and connective tissues. Its unique cyclic structure provides stability to collagen's triple helix, making it a critical marker for collagen synthesis and degradation. This compound is essential for manufacturers in the pharmaceutical, nutraceutical, cosmetic, and biomedical research sectors, where collagen health and integrity are paramount.

Application

• Pharmaceutical Intermediates: Used in the synthesis of drugs targeting connective tissue disorders, wound healing, and bone health.
• Nutraceutical & Dietary Supplements: A vital ingredient in collagen peptides, joint health formulas, and skin rejuvenation supplements.
• Cosmetic & Skincare Formulations: Incorporated into anti-aging creams, serums, and lotions to promote skin elasticity and hydration.
• Biomedical & Life Science Research: Serves as a biochemical marker for collagen metabolism studies, tissue engineering, and cell culture applications.
• Animal Nutrition: Used in specialized feed for pets and livestock to support joint and connective tissue health.
• Food Science: Employed in research related to meat tenderness and gelatin quality.

Basic Information

Product Name	Hydroxyproline
CAS No.	6912-67-0
Molecular Formula	C5H9NO3
Molecular Weight	131.13 g/mol
Synonyms	L-Hydroxyproline; (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid; 4-Hydroxy-L-proline; Hyp; Oxoproline; L-4-Hydroxyproline; trans-4-Hydroxy-L-proline
EINECS	230-035-2

Quality Control

Our Hydroxyproline is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and stringent controls for residual solvents and heavy metals. Certificates of Analysis (COA) confirming compliance with USP, EP, and FCC grade specifications, where applicable, are provided to ensure traceability and product confidence for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.5%
Specific Rotation	-74° to -78° (c=1 in H2O)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.