Description

(2S)-2-Amino-3-Hydroxy-Propanoic Acid is the L-enantiomer of serine, a fundamental non-essential amino acid crucial for protein biosynthesis and numerous metabolic pathways. Its high purity and defined stereochemistry make it a critical building block for producing pharmaceuticals, peptides, and advanced biochemical reagents. This compound is essential for research and manufacturing in the pharmaceutical, biotechnology, and nutraceutical industries, where precise molecular structure is paramount for efficacy and safety.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), especially antibiotics, antivirals, and enzyme inhibitors.
• Peptide Synthesis: Serves as a protected amino acid residue in solid-phase and solution-phase peptide synthesis for research and therapeutic peptides.
• Cell Culture Media: Used as a component in defined cell culture media and fermentation broths to support the growth of mammalian and bacterial cells.
• Biochemical Research: Employed as a standard, substrate, or precursor in enzymatic studies, metabolic research, and nutritional science.
• Nutraceuticals & Supplements: Incorporated into specialized amino acid formulations and infusion solutions for clinical nutrition.
• Cosmetic Ingredients: Utilized in the formulation of skin-care products for its role as a natural moisturizing factor (NMF) precursor.

Basic Information

Product Name	(2S)-2-Amino-3-Hydroxy-Propanoic Acid
CAS No.	6898-95-9
Molecular Formula	C3H7NO3
Molecular Weight	105.09 g/mol
Synonyms	L-Serine; (S)-Serine; Ser; (2S)-2-Amino-3-hydroxypropanoic acid; (S)-2-Amino-3-hydroxypropionic acid; 3-Hydroxy-L-alanine; β-Hydroxy-L-alanine; L-(-)-Serine
EINECS	200-274-3

Quality Control

Our (2S)-2-Amino-3-Hydroxy-Propanoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets high-grade specifications suitable for pharmaceutical and research applications. Certificates of Analysis (COA) documenting identity, purity, and specific tests are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.5%
Optical Rotation [α]20/D	-6.8° to -7.8° (c=1 in H2O)
Specific Rotation	-14.0° to -16.0° (c=8 in 5N HCl)
Loss on Drying	≤ 0.5%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Chiral Purity (Enantiomeric Excess)	≥ 99.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.