Description

(3R)-1,2,3,3Aα,4,5,6,6Aβ,7,7Aβ,8,9,10,12Aα-Tetradecahydro-3β-Hydroxy-5α-Methyl-11H-Pyrido[1',2':3,4]Pyrimido[2,1,6-De]Quinolizin-11-One is a complex, high-purity alkaloid derivative with a defined stereochemistry, serving as a critical advanced pharmaceutical intermediate and a valuable scaffold in medicinal chemistry research. Its intricate polycyclic structure makes it a versatile building block for the synthesis of novel bioactive compounds targeting the central nervous system and other therapeutic areas. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new drug candidates and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of complex drug molecules, particularly those with neurological activity.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the design of new chemical entities (NCEs).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Investigated for its potential interactions with biological targets such as receptors or enzymes in academic and industrial research settings.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecular architectures for specialty applications.

Basic Information

Product Name	(3R)-1,2,3,3Aα,4,5,6,6Aβ,7,7Aβ,8,9,10,12Aα-Tetradecahydro-3β-Hydroxy-5α-Methyl-11H-Pyrido[1',2':3,4]Pyrimido[2,1,6-De]Quinolizin-11-One
CAS No.	6871-55-2
Molecular Formula	C19H26N2O2
Molecular Weight	314.42 g/mol
Synonyms	11H-Pyrido[1',2':3,4]pyrimido[2,1,6-de]quinolizin-11-one, 1,2,3,3aα,4,5,6,6aβ,7,7aβ,8,9,10,12aα-tetradecahydro-3β-hydroxy-5α-methyl-, (3R)-; (3R)-Tetradecahydro-3β-hydroxy-5α-methyl-11H-pyrido[1',2':3,4]pyrimido[2,1,6-de]quinolizin-11-one; 3β-Hydroxy-5α-methyl-11-oxohexacyclo[7.7.0.0²,⁷.0³,¹⁶.0⁴,¹⁵.0⁸,¹³]hexadec-14-en-10-yl]ethan-1-aminium (IUPAC alternative); Alkaloid derivative intermediate; Complex polycyclic amine.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development and commercial projects with specifications that can meet GMP or research-grade requirements as needed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.