Description

H-Ala-Ala-D-Ala-Oh CAS NO 6745-19-3 is a synthetic tripeptide derivative featuring a D-alanine residue, making it a valuable chiral building block and research chemical. This compound is essential for advanced biochemical research, particularly in the study of enzyme specificity, peptide stability, and antimicrobial mechanisms. It is primarily utilized by pharmaceutical R&D laboratories, academic institutions, and fine chemical manufacturers focused on peptide synthesis and proteomics.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Studies: Used as a substrate or inhibitor in enzymatic assays to study protease activity and specificity.
• Antimicrobial Peptide (AMP) Research: Serves as a model compound for investigating structure-activity relationships in peptides with potential antibiotic properties.
• Chiral Synthesis: Employed as a building block in asymmetric synthesis due to the presence of the D-alanine configuration.
• Proteomics & Mass Spectrometry: Acts as a standard or reference material in analytical method development for peptide analysis.
• Academic & Institutional Research: A critical reagent for graduate-level and post-doctoral research in medicinal chemistry and biochemistry.

Basic Information

Item	Details
Product Name	H-Ala-Ala-D-Ala-Oh
CAS No.	6745-19-3
Molecular Formula	C9H17N3O4
Molecular Weight	231.25 g/mol
Synonyms	L-Alanyl-L-alanyl-D-alanine; Ala-Ala-D-Ala; H-Ala-Ala-D-Ala-OH; Tripeptide Ala-Ala-D-Ala; (2R)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]propanoyl]amino]propanoic acid; D-Alanine, L-alanyl-L-alanyl-; AAD; AAD tripeptide
EINECS	Contact for details

Quality Control

Our H-Ala-Ala-D-Ala-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via mass spectrometry and IR spectroscopy. We provide Certificates of Analysis (COA) with detailed results for all critical parameters, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (D-Ala content)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.