Description

H-D-Glu(Gly-Oh)-Oh is a protected dipeptide derivative, specifically a glutamic acid residue linked to glycine, where the side-chain carboxyl group of glutamic acid is protected. This compound is a crucial building block in the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced peptide chemistry, drug discovery, and the development of novel therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled assembly of peptide chains in automated synthesizers.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs targeting various diseases.
• Bioconjugation: Serves as a linker or spacer molecule for attaching peptides to other biomolecules, polymers, or surfaces.
• Chemical Biology Probes: Integral in creating labeled or modified peptides for studying protein-protein interactions and cellular processes.
• Custom Peptide Manufacturing: A fundamental raw material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke peptides.
• Academic Research: Employed in university laboratories for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	H-D-Glu(Gly-Oh)-Oh
CAS No.	6729-55-1
Molecular Formula	C7H12N2O6
Molecular Weight	220.18 g/mol
Synonyms	H-D-Glu(α-Gly)-OH; (2S)-2-[[(2-Aminoacetyl)amino]pentanedioic acid; D-Glutamic acid, N-glycyl-; Glycyl-D-glutamic acid; N-Glycyl-D-glutamic acid; D-Glu-Gly; D-Glutamylglycine; Boc-D-Glu(OBzl)-Gly-OH (related protected form)
EINECS	Contact for details

Quality Control

Our H-D-Glu(Gly-Oh)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.