Description

Pht-Gly-Leu-Oh CAS NO 6707-71-7 is a protected tripeptide derivative, specifically N-Phthaloylglycyl-L-leucine, serving as a crucial synthetic intermediate in advanced organic and peptide chemistry. This compound is valued for its role in constructing more complex peptide sequences, where the phthaloyl (Pht) group acts as a temporary protecting group for the amino terminus, allowing for selective deprotection and further chain elongation. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of bioactive peptides, novel drug candidates, and specialized biochemical tools.

Application

• Pharmaceutical Intermediate: Key building block in the solid-phase and solution-phase synthesis of therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a standard or reagent in studies exploring enzyme-substrate interactions, protease specificity, and peptide metabolism.
• Fine Chemical Synthesis: Intermediate for producing custom peptides, amino acid derivatives, and molecular probes for diagnostic applications.
• Academic Research: Employed in university and institutional labs for teaching advanced peptide coupling techniques and protecting group strategies.
• Cosmetic Peptide Development: Potential raw material in the research and development of synthetic peptides for cosmetic and dermatological formulations.

Basic Information

Product Name	Pht-Gly-Leu-Oh
CAS No.	6707-71-7
Molecular Formula	C₁₇H₂₀N₂O₅
Molecular Weight	332.35 g/mol
Synonyms	N-Phthaloylglycyl-L-leucine; N-(Phthaloylglycyl)-L-leucine; Phthaloylglycylleucine; L-Leucine, N-(N-phthaloylglycyl)-; Phthalimidoacetyl-L-leucine; Pht-Gly-Leu-OH; PGLEU; NSC 334718
EINECS	Contact for details

Quality Control

Our Pht-Gly-Leu-Oh is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.