Description

2,4,6-Trichloro-5-Fluoropyrimidine is a versatile and highly functionalized heterocyclic building block, essential for advanced organic synthesis. Its unique halogenated structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides due to its reactive halogen sites.
• Material Science Research: Serves as a building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination to introduce the pyrimidine core.
• Nucleoside & Nucleotide Chemistry: Used in the modification and synthesis of fluorinated nucleoside analogs for medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production in fine chemical manufacturing.

Basic Information

Product Name	2,4,6-Trichloro-5-Fluoropyrimidine
CAS No.	6693-08-9
Molecular Formula	C4Cl3FN2
Molecular Weight	201.41 g/mol
Synonyms	5-Fluoro-2,4,6-trichloropyrimidine; 2,4,6-Trichloro-5-fluoropyrimidine; 5-Fluoropyrimidine-2,4,6-triyl trichloride; Trichlorofluoropyrimidine; NSC 5235; Fluorotrichloropyrimidine; Pyrimidine, 2,4,6-trichloro-5-fluoro-
EINECS	Contact for details

Quality Control

Our 2,4,6-Trichloro-5-Fluoropyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.