Description

4,6-Dichloro-5-Fluoro-2-(Methylsulfanyl)Pyrimidine is a high-value halogenated pyrimidine building block essential for advanced organic synthesis. This compound matters for its role as a key synthetic intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables precise molecular construction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce complex heterocyclic scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and kinase inhibitor research.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides that require fluorinated pyrimidine cores for enhanced activity.
• Chemical Research & Development: Serves as a versatile scaffold for constructing complex heterocyclic libraries in medicinal and combinatorial chemistry.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the commercial-scale production of fluoropyrimidine-based active pharmaceutical ingredients.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for catalysis due to its electron-deficient aromatic system.

Basic Information

Product Name	4,6-Dichloro-5-Fluoro-2-(Methylsulfanyl)Pyrimidine
CAS No.	6693-07-8
Molecular Formula	C5H3Cl2FN2S
Molecular Weight	213.06 g/mol
Synonyms	2-(Methylthio)-4,6-dichloro-5-fluoropyrimidine; 5-Fluoro-4,6-dichloro-2-methylsulfanylpyrimidine; 4,6-Dichloro-5-fluoro-2-methylmercaptopyrimidine; 4,6-Dichloro-5-fluoro-2-(methylthio)pyrimidine; 2-Methylsulfanyl-4,6-dichloro-5-fluoropyrimidine; 6693-07-8; 4,6-Dichloro-5-fluoro-2-(methylsulfanyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-5-Fluoro-2-(Methylsulfanyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.