Description

Cyclo(-Phe-Trp) CAS NO 6521-48-8 is a synthetic cyclic dipeptide composed of phenylalanine and tryptophan residues. This compound is of significant interest in pharmaceutical research and development due to its potential as a scaffold for bioactive molecules and its role in studying peptide conformation and stability. It serves as a critical intermediate and reference standard for researchers in medicinal chemistry, biochemistry, and peptide synthesis. The product is supplied with a focus on high purity and batch-to-batch consistency to support rigorous scientific applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex peptide-based drug candidates and pharmacologically active compounds.
• Medicinal Chemistry Research: Used as a molecular scaffold to explore structure-activity relationships (SAR) and develop new therapeutic agents.
• Biochemical Research: Employed in studies of peptide folding, cyclization kinetics, and the stability of cyclic dipeptide structures.
• Reference Standard: Provides a high-purity benchmark for analytical method development, validation, and quality control in laboratory settings.
• Peptide Library Synthesis: A valuable component in combinatorial chemistry for creating diverse libraries of cyclic peptides for screening.
• Academic & Institutional Research: Supports fundamental research in universities and institutes focusing on organic synthesis and peptide science.

Basic Information

Product Name	Cyclo(-Phe-Trp)
CAS No.	6521-48-8
Molecular Formula	C20H19N3O2
Molecular Weight	333.39 g/mol
Synonyms	Cyclo(L-phenylalanyl-L-tryptophyl); Cyclo(Phe-Trp); L-Phenylalanyl-L-tryptophan anhydride; 3-Benzyl-6-(1H-indol-3-ylmethyl)piperazine-2,5-dione; DKPs (Diketopiperazines) derivative; c(Phe-Trp); Cyclo(Phe-Trp) dipeptide
EINECS	Contact for details

Quality Control

Our Cyclo(-Phe-Trp) is manufactured under strict quality management systems to ensure the highest standards of purity and identity. Each batch is subjected to comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting the exact specifications and test results. Our quality commitment aligns with the rigorous requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.