Description

Theophylline, 8-[(Benzylthio)Methyl] is a specialized xanthine derivative, chemically modified with a benzylthio-methyl group at the 8-position. This structural modification imparts unique physicochemical properties, making it a valuable intermediate for advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for synthesizing novel therapeutic agents and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel xanthine-based drug candidates targeting respiratory and cardiovascular diseases.
• Biochemical Research: Used as a reference standard or probe in enzymatic studies related to phosphodiesterase (PDE) inhibition.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Process Chemistry: Employed in route scouting and scale-up optimization for the production of high-value active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for investigating new therapeutic pathways and molecular mechanisms.

Basic Information

Product Name	Theophylline, 8-[(Benzylthio)Methyl]
CAS No.	6466-43-9
Molecular Formula	C15H16N4O2S
Molecular Weight	316.38 g/mol
Synonyms	8-[(Benzylthio)methyl]theophylline; 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-8-[[(phenylmethyl)thio]methyl]-; 8-(Benzylthiomethyl)theophylline; Theophylline Derivative (Benzylthio); 1,3-Dimethyl-8-((benzylthio)methyl)xanthine; 8-(Benzylsulfanylmethyl)-1,3-dimethyl-7H-purine-2,6-dione
EINECS	Contact for details

Quality Control

Every batch of Theophylline, 8-[(Benzylthio)Methyl] is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.