Description

6-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Sulfonyl Chloride is a specialized sulfonyl chloride derivative of a pyrimidine base, serving as a critical high-purity building block in advanced organic synthesis. Its core value lies in its dual functionality, acting as a reactive sulfonylation agent and a heterocyclic scaffold for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analogs, antiviral agents, and other bioactive heterocyclic compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of activity-based probes targeting specific enzymes.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials with specific sulfonamide linkages.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring precise sulfonylation on a pyrimidine core.
• Academic & Industrial R&D: Fundamental reagent for methodological development in organic chemistry and exploring new reaction pathways.

Basic Information

Product Name	6-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Sulfonyl Chloride
CAS No.	6461-30-9
Molecular Formula	C5H5ClN2O4S
Molecular Weight	224.62 g/mol
Synonyms	5-Sulfonylchloride-6-methyluracil; 6-Methyluracil-5-sulfonyl chloride; 5-(Chlorosulfonyl)-6-methyl-2,4(1H,3H)-pyrimidinedione; 6-Methyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinesulfonyl chloride; 6-Methylbarbituric acid-5-sulfonyl chloride; 5-Chlorosulfonyl-6-methyluracil; Methyluracil sulfonyl chloride
EINECS	229-256-6

Quality Control

Our production of 6-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Sulfonyl Chloride adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Every lot is fully characterized and tested against comprehensive specifications. A detailed Certificate of Analysis (COA) providing identity, purity (typically ≥97% by HPLC), and impurity profile is supplied with each shipment, ensuring it meets the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.