Description

2-(4-Fluoro-Phenyl)-Acetamidine Hcl is a high-purity organic intermediate featuring a fluorinated phenyl ring and an amidine functional group. This compound is valued for its role as a critical building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Chemical Research: Serves as a versatile building block in academic and industrial laboratories for heterocyclic chemistry and the development of novel chemical entities.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for metal complexes and catalysts used in asymmetric synthesis.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and performance materials.

Basic Information

Product Name	2-(4-Fluoro-Phenyl)-Acetamidine Hcl
CAS No.	6437-40-7
Molecular Formula	C8H10ClFN2
Molecular Weight	188.63 g/mol
Synonyms	2-(4-Fluorophenyl)acetamidine hydrochloride; 4-Fluorobenzeneacetamidine hydrochloride; (4-Fluorophenyl)acetamidine HCl; 2-(p-Fluorophenyl)acetamidine hydrochloride; α-(4-Fluorophenyl)acetamidine hydrochloride; Acetamidine, 2-(4-fluorophenyl)-, hydrochloride; 6437-40-7
EINECS	Contact for details

Quality Control

Our 2-(4-Fluoro-Phenyl)-Acetamidine Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry for identity confirmation and impurity profiling. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.