Description

Z-Gly-Gly-NH2 is a protected dipeptide derivative, specifically the benzyloxycarbonyl (Z) protected form of glycylglycine amide. This compound serves as a crucial building block in peptide synthesis, offering a protected N-terminus and a reactive C-terminal amide group for further chain elongation. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers involved in developing novel peptide-based therapeutics and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key intermediate for incorporating the Gly-Gly sequence into longer peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies to construct specific peptide sequences.
• Pharmaceutical Research: A precursor in the development of peptide drugs, enzyme inhibitors, and diagnostic agents.
• Bioconjugation: The reactive amide group can be utilized for linking peptides to other molecules, surfaces, or carriers.
• Biochemical Tool Development: Used to create substrates for protease and peptidase enzyme studies.
• Academic Research: A standard reagent in university and institutional labs for teaching and exploring peptide chemistry.

Basic Information

Product Name	Z-Gly-Gly-NH2
CAS No.	6422-35-1
Molecular Formula	C12H15N3O4
Molecular Weight	265.27 g/mol
Synonyms	Nα-Carbobenzoxy-glycylglycinamide; N-Cbz-Gly-Gly-NH2; Z-Gly-Glycinamide; Benzyloxycarbonyl-glycyl-glycine amide; CBZ-Gly-Gly-NH2; Nα-[(Benzyloxy)carbonyl]glycylglycinamide; Glycine, N-[(phenylmethoxy)carbonyl]glycyl-, amide
EINECS	229-193-4

Quality Control

Our Z-Gly-Gly-NH2 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and related substance profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.