Description

2,3-Difluorophenol is a versatile fluorinated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Building block for advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the development of fluorinated components for electronic displays and organic light-emitting diodes to improve performance and durability.
• Polymer & Resin Modifier: Incorporated into high-performance polymers (e.g., polyarylates, polyetherketones) to enhance thermal stability, chemical resistance, and dielectric properties.
• Organic Synthesis Reagent: Serves as a versatile starting material or coupling partner in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for complex molecule assembly.
• Chemical Research & Development: Fundamental reagent in academic and industrial R&D for exploring new fluorination chemistry and structure-activity relationships.

Basic Information

Product Name	2,3-Difluorophenol
CAS No.	6418-38-8
Molecular Formula	C6H4F2O
Molecular Weight	130.09 g/mol
Synonyms	2,3-Difluorophenol; 2,3-DFP; 1-Hydroxy-2,3-difluorobenzene; 2,3-Difluoro-1-hydroxybenzene; o,m-Difluorophenol; Phenol, 2,3-difluoro-; 2,3-Difluorphenol; NSC 406924
EINECS	229-133-5

Quality Control

Our 2,3-Difluorophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure it meets the highest purity and consistency standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.