Description

Leucylproline CAS NO 6403-35-6 is a high-purity dipeptide composed of the amino acids leucine and proline. This compound is valued for its role as a key intermediate in peptide synthesis and biochemical research, offering precise structural control. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic laboratories engaged in proteomics, drug discovery, and the development of bioactive peptides.

Application

• Pharmaceutical Intermediate: A critical building block for the solid-phase and solution-phase synthesis of complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, particularly those involving dipeptidyl peptidases (DPP) and other proteases.
• Proteomics & Metabolic Studies: Serves as a reference compound in mass spectrometry and chromatography for identifying and quantifying peptides in biological samples.
• Nutraceutical Development: Investigated for potential applications in functional food and dietary supplement formulations targeting metabolic health.
• Cosmetic Peptide Synthesis: Acts as a precursor in the manufacture of specialized peptides for advanced skincare and anti-aging formulations.

Basic Information

Product Name	Leucylproline
CAS No.	6403-35-6
Molecular Formula	C11H20N2O3
Molecular Weight	228.29 g/mol
Synonyms	L-Leucyl-L-proline; Leu-Pro; L-Leu-L-Pro; H-Leu-Pro-OH; (S)-2-((S)-2-Amino-4-methylpentanamido)pyrrolidine-1-carboxylic acid; NSC 334358; Proline, L-leucyl-; Leucineproline
EINECS	Contact for details

Quality Control

Our Leucylproline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: -70° to -80° (c=1 in H₂O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.