Description

n-Methyl-D-Aspartic Acid is a high-purity, non-proteinogenic amino acid derivative of D-aspartic acid. This compound is a crucial selective NMDA receptor agonist, making it an indispensable research tool in neuroscience and pharmacology. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and manufacturers of fine chemicals and biochemical reagents.

Application

• Neuroscience Research: As a selective agonist for NMDA (N-methyl-D-aspartate) receptors, it is used to study excitatory neurotransmission, synaptic plasticity, and neurological disorders.
• Pharmacological Studies: Employed in the screening and development of novel neuroprotective agents, antidepressants, and drugs targeting glutamate pathways.
• Biochemical Reagent: Serves as a key intermediate or reference standard in the synthesis of more complex neuroactive compounds and peptides.
• Cell Culture & Physiology: Used in experimental protocols to stimulate NMDA receptors in neuronal cell cultures and tissue preparations.
• Diagnostic Development: Potential use in the development of assays and kits for neurological research and diagnostic applications.

Basic Information

Product Name	n-Methyl-D-Aspartic Acid
CAS No.	6384-92-5
Molecular Formula	C5H9NO4
Molecular Weight	147.13 g/mol
Synonyms	N-Methyl-D-aspartic acid; NMDA; (R)-2-(Methylamino)succinic acid; D-N-Methylaspartic acid; (2R)-2-(Methylamino)butanedioic acid; Methyl-D-aspartate; NMDA agonist
EINECS	228-974-5

Quality Control

Our n-Methyl-D-Aspartic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the exacting standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Specific range provided on COA
Chiral Purity	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.