Description

L-Asparagine Methyl Ester Hydrochloride is a protected derivative of the amino acid L-asparagine, widely utilized as a key chiral building block in organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the development of pharmaceuticals, peptides, and bioactive molecules. Its primary value lies in providing a controlled, reactive site for the construction of complex molecular architectures, making it indispensable for the pharmaceutical, biotechnology, and advanced chemical synthesis sectors.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for peptide-based drugs and enzyme inhibitors.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Biochemical Research: Used in proteomics and metabolic pathway studies as a standard or reagent.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material for the preparation of enantiomerically pure compounds.
• Agrochemical Development: Employed in the research and synthesis of novel, biologically active crop protection agents.
• Diagnostic Reagents: A component in the formulation of specialized diagnostic kits and assays.

Basic Information

Product Name	L-Asparagine Methyl Ester Hydrochloride
CAS No.	6384-09-4
Molecular Formula	C5H11ClN2O3
Molecular Weight	182.61 g/mol
Synonyms	L-Asparagine methyl ester HCl; Methyl L-asparaginate hydrochloride; (S)-2-Amino-3-carbamoylpropanoic acid methyl ester hydrochloride; H-Asn-OMe·HCl; Asparagine methyl ester HCl; L-2-Aminosuccinamic acid 4-methyl ester hydrochloride; Methyl (2S)-2-amino-3-carbamoylpropanoate hydrochloride
EINECS	Contact for details

Quality Control

Our L-Asparagine Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under dry conditions to prevent product degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	+15.0° to +20.0° (c=1 in H₂O)
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.