Description

6-Mercapto-4(1H)-Pyrimidinone is a versatile heterocyclic building block and key intermediate in organic synthesis. This compound is valued for its reactive thiol and carbonyl groups, which enable its use in constructing complex molecular architectures. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of nucleoside analogs, antiviral agents, and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential building block for creating functional polymers, ligands for metal complexes, and advanced organic materials.
• Bioconjugation Chemistry: The thiol group can be utilized for site-specific modification of proteins and other biomolecules.

Basic Information

Product Name	6-Mercapto-4(1H)-Pyrimidinone
CAS No.	6311-83-7
Molecular Formula	C4H4N2OS
Molecular Weight	128.15 g/mol
Synonyms	4-Hydroxy-2-mercaptopyrimidine; 2-Mercapto-4-hydroxypyrimidine; 4-Pyrimidinol, 2-mercapto-; 6-Mercapto-4-pyrimidinol; 2-Thiouracil (tautomer); 4-Hydroxy-2(1H)-pyrimidinethione; 2-Mercapto-4(1H)-pyrimidinone; 4-Hydroxy-2-pyrimidinethiol
EINECS	228-639-1

Quality Control

Our 6-Mercapto-4(1H)-Pyrimidinone is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.