Description

2-Amino-6-Chloro-1H-Pyrimidine-4-Thione is a versatile heterocyclic building block characterized by its reactive thione and chloro substituents. This compound matters as a critical intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists for creating novel active ingredients, including potential antiviral and anticancer agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of nucleoside analogs and other bioactive heterocycles with potential antiviral or antitumor activity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Organic Synthesis Building Block: Serves as a versatile precursor for further functionalization, including nucleophilic substitution reactions at the chloro position and modifications of the thione group.
• Material Science Research: Investigated for the development of novel organic ligands and coordination complexes in catalysis.
• Biochemical Research: Utilized in studies involving enzyme inhibition or as a scaffold for designing molecular probes.

Basic Information

Product Name	2-Amino-6-Chloro-1H-Pyrimidine-4-Thione
CAS No.	6310-02-7
Molecular Formula	C4H4ClN3S
Molecular Weight	161.61 g/mol
Synonyms	6-Chloro-2-amino-4-mercaptopyrimidine; 2-Amino-6-chloro-4-mercaptopyrimidine; 2-Amino-6-chloro-4-pyrimidinethiol; 6-Chloro-2-aminopyrimidine-4-thiol; 2-Amino-6-chloro-4(1H)-pyrimidinethione; 4(1H)-Pyrimidinethione, 2-amino-6-chloro-; 4-Mercapto-6-chloro-2-aminopyrimidine; 6-Chloro-2-aminopyrimidine-4(3H)-thione
EINECS	228-636-5

Quality Control

Our 2-Amino-6-Chloro-1H-Pyrimidine-4-Thione is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.