Description

L-Valine Methyl Ester Hydrochloride CAS NO 6306-52-1 is a protected amino acid derivative, specifically the methyl ester hydrochloride salt of L-Valine. This compound is a crucial chiral building block in organic synthesis, valued for its role in introducing the valine moiety while protecting the carboxylic acid group. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the synthesis of peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) as a protected amino acid building block.
• Biochemical Research: Serves as a precursor in metabolic studies and for the preparation of labeled compounds for research.
• Prodrug Development: Employed in the design and synthesis of ester-based prodrugs to enhance drug bioavailability.
• Agrochemical Synthesis: Acts as an intermediate in the production of certain chiral agrochemicals and pesticides.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.

Basic Information

Product Name	L-Valine Methyl Ester Hydrochloride
CAS No.	6306-52-1
Molecular Formula	C6H14ClNO2
Molecular Weight	167.63 g/mol
Synonyms	L-Valine methyl ester HCl; (S)-2-Amino-3-methylbutanoic acid methyl ester hydrochloride; Methyl L-valinate hydrochloride; Val-OMe·HCl; H-Val-OMe·HCl; (S)-Valine methyl ester hydrochloride; L-2-Amino-3-methylbutyric acid methyl ester hydrochloride; L-α-Aminoisovaleric acid methyl ester hydrochloride
EINECS	228-590-7

Quality Control

Our L-Valine Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and synthesis. Specifications typically cover identity, assay, enantiomeric purity, and related substances. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]	+15.0° to +25.0° (c=1 in H2O)
Enantiomeric Purity (HPLC)	≥99.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.