Description

4-[(2-Amino-5-Bromo-6-Methyl-Pyrimidin-4-Yl)Amino]Benzonitrile CAS NO 6303-42-0 is a high-purity, advanced pharmaceutical intermediate featuring a unique pyrimidine-benzonitrile hybrid structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other targeted small-molecule therapeutics.
• Agrochemical Research: Serves as a building block for developing new fungicides and herbicides with specific modes of action.
• Chemical Synthesis: Used in organic synthesis for constructing complex heterocyclic compounds in medicinal chemistry programs.
• Life Science Research: Employed in biochemical research as a tool compound for studying enzyme interactions and signaling pathways.
• Material Science: Potential intermediate for the development of organic electronic materials and specialty dyes.

Basic Information

Product Name	4-[(2-Amino-5-Bromo-6-Methyl-Pyrimidin-4-Yl)Amino]Benzonitrile
CAS No.	6303-42-0
Molecular Formula	C12H11BrN6
Molecular Weight	319.16 g/mol
Synonyms	4-[(2-Amino-5-bromo-6-methyl-4-pyrimidinyl)amino]benzonitrile; 4-[(2-Amino-5-bromo-6-methylpyrimidin-4-yl)amino]benzonitrile; 4-(2-Amino-5-bromo-6-methylpyrimidin-4-ylamino)benzonitrile; Benzonitrile, 4-[(2-amino-5-bromo-6-methyl-4-pyrimidinyl)amino]-; 6303-42-0; 4-(2-Amino-5-bromo-6-methyl-pyrimidin-4-ylamino)-benzonitrile
EINECS	Contact for details

Quality Control

Our production of 4-[(2-Amino-5-Bromo-6-Methyl-Pyrimidin-4-Yl)Amino]Benzonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D and scale-up. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.