Description

1-(4-Chlorophenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is a high-purity heterocyclic organic compound belonging to the pyrazolopyrimidine class. This advanced pharmaceutical intermediate is valued for its role as a critical building block in the synthesis of targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a reference standard and active scaffold in structure-activity relationship (SAR) studies and high-throughput screening.
• API Development: Serves as a core structural moiety in the development and scale-up of new active pharmaceutical ingredients (APIs).
• Academic & Contract Research: Employed in university laboratories and CROs (Contract Research Organizations) for medicinal chemistry and drug discovery programs.

Basic Information

Product Name	1-(4-Chlorophenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine
CAS No.	6289-04-9
Molecular Formula	C11H8ClN5
Molecular Weight	245.67 g/mol
Synonyms	4-Amino-1-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine; 1-(p-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; PP1 Analog; 4-Amino-1-(4'-chlorophenyl)pyrazolo[3,4-d]pyrimidine; CAS 6289-04-9; 1-(4-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine
EINECS	Contact for details

Quality Control

Our 1-(4-Chlorophenyl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.