Description

3-Phenyl-L-Serine is a non-proteinogenic amino acid derivative featuring a phenyl substituent on the serine backbone. This compound matters as a versatile chiral building block, enabling the synthesis of complex molecules with high stereochemical purity for advanced research and development. It is primarily needed by pharmaceutical researchers, peptide chemists, and fine chemical manufacturers developing novel therapeutics, bioactive peptides, and specialized catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptide Synthesis: Used to incorporate phenyl-serine motifs into custom peptides to modulate their stability, bioavailability, and receptor binding affinity.
• Biochemical Research: Serves as a precursor or standard in enzymatic studies and metabolic pathway investigations.
• Asymmetric Catalysis: Employed as a ligand or precursor for chiral catalysts used in stereoselective organic transformations.
• Fine Chemical Production: A building block for the manufacture of advanced materials, specialty surfactants, and complex natural product analogs.

Basic Information

Product Name	3-Phenyl-L-Serine
CAS No.	6254-48-4
Molecular Formula	C9H11NO3
Molecular Weight	181.19 g/mol
Synonyms	(2S)-2-Amino-3-hydroxy-3-phenylpropanoic acid; L-3-Phenylserine; (S)-2-Amino-3-hydroxy-3-phenylpropionic acid; β-Hydroxy-L-phenylalanine; L-β-Phenylserine; H-PhSer-OH; (S)-3-Phenylserine; L-3-Phenylserine
EINECS	228-403-9

Quality Control

Our 3-Phenyl-L-Serine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by IR and NMR. We provide Certificates of Analysis (COA) with detailed specifications for trace metals, residual solvents, and related substances. Our quality commitment ensures the material is suitable for demanding applications in pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation and clumping.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.