Description

L-2-Methylglutamic Acid is a non-proteinogenic amino acid derivative of glutamic acid, featuring a methyl group substitution at the α-carbon. This structural modification makes it a valuable chiral building block and intermediate in organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel compounds, including potential drug candidates and bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic targets.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate metabolic pathways involving glutamate analogs.
• Peptide Synthesis: Employed as a modified amino acid residue in the synthesis of specialized peptides to alter their stability, conformation, or biological activity.
• Agrochemical Development: Acts as an intermediate in the synthesis of novel herbicides, pesticides, or plant growth regulators.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	L-2-Methylglutamic Acid
CAS No.	6208-95-3
Molecular Formula	C6H11NO4
Molecular Weight	161.16 g/mol
Synonyms	(2S)-2-Aminopentanedioic acid; (S)-2-Methylglutamic acid; L-α-Methylglutamic acid; (S)-2-Methyl-2-aminopentanedioic acid; 2-Methyl-L-glutamic acid; (2S)-2-Methylglutamic acid; L-2-Methylglutamate; (S)-2-Aminopentanedioic acid
EINECS	Contact for details

Quality Control

Our L-2-Methylglutamic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity, identity, and specific impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.