Description

(2R,3S)-3-Methylglutamic Acid CAS NO 6208-94-2 is a high-purity, stereochemically defined non-proteinogenic amino acid derivative. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, particularly for pharmaceuticals and bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries requiring precise stereochemistry for drug development and process chemistry.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, especially in neurological and metabolic disorder research.
• Peptide Mimetics & Modifications: Used to incorporate non-natural amino acid residues into peptides to alter stability, bioavailability, and biological activity.
• Agrochemical Research: Serves as a precursor for developing chiral active ingredients with specific modes of action.
• Biochemical Research: Tool compound for studying enzyme mechanisms, such as those involving glutamate analogs, and receptor binding studies.
• Fine Chemical Synthesis: Building block for complex natural product synthesis and specialty chemicals requiring defined stereocenters.
• Diagnostic Reagent Development: Potential use in developing assays and probes targeting glutamate-related pathways.

Basic Information

Product Name	(2R,3S)-3-Methylglutamic Acid
CAS No.	6208-94-2
Molecular Formula	C6H11NO4
Molecular Weight	161.16 g/mol
Synonyms	(2R,3S)-3-Methyl-L-glutamic Acid; (2R,3S)-3-Methylglutamate; (2R,3S)-3-MGA; 3-Methyl-DL-glutamic Acid (stereoisomer mixture); (2R,3S)-2-Amino-3-methylpentanedioic Acid; β-Methylglutamic Acid; 3-Methylglutamic Acid
EINECS	Contact for details

Quality Control

Our (2R,3S)-3-Methylglutamic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (diastereomeric excess)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.