Description

1-(3'-Bromo-3'-Deoxyarabinofuranosyl)Uracil CAS NO 6206-18-4 is a modified nucleoside analog, a key synthetic intermediate in medicinal chemistry and life science research. Its primary value lies in its role as a versatile building block for the synthesis of novel antiviral and anticancer nucleoside analogs, enabling the exploration of structure-activity relationships. This high-purity compound is essential for pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on developing targeted therapeutics.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel antiviral and anticancer nucleoside drugs.
• Antiviral Drug Research: Used in the development of nucleoside analogs targeting viral polymerases, particularly for herpesviruses and other DNA viruses.
• Anticancer Agent Development: Serves as a precursor for creating nucleoside-based chemotherapeutic agents that interfere with DNA synthesis in rapidly dividing cells.
• Biochemical Probe Synthesis: Utilized to create labeled or modified nucleosides for studying enzyme mechanisms, such as those of thymidine kinase.
• Life Science Research: A valuable tool in academic and industrial research for investigating nucleoside metabolism and designing novel bioactive molecules.
• Process Chemistry & Scale-Up: Employed in the development and optimization of synthetic routes for active pharmaceutical ingredients (APIs) at various scales.

Basic Information

Product Name	1-(3'-Bromo-3'-Deoxyarabinofuranosyl)Uracil
CAS No.	6206-18-4
Molecular Formula	C9H11BrN2O6
Molecular Weight	323.10 g/mol
Synonyms	3'-Bromo-3'-deoxyarabinofuranosyluracil; 3'-Bromo-ara-U; 1-(3-Bromo-3-deoxy-β-D-arabinofuranosyl)uracil; 3'-Bromo-3'-deoxy-β-D-arabinofuranosyluracil; Br-araU; 3'-Bromouridine arabinoside; Uracil, 1-(3-bromo-3-deoxy-β-D-arabinofuranosyl)-; 3'-Bromo-1-(β-D-arabinofuranosyl)uracil
EINECS	Contact for details

Quality Control

Our 1-(3'-Bromo-3'-Deoxyarabinofuranosyl)Uracil is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.