Description

L-Tryptophan Monohydrochloride is the hydrochloride salt form of the essential amino acid L-Tryptophan, offering enhanced stability and solubility for precise formulation. This high-purity compound is critical for applications demanding strict control over amino acid content and bioavailability. It serves as a vital raw material and biochemical intermediate for the pharmaceutical, nutraceutical, and research sectors, where consistent quality is paramount for product efficacy and regulatory compliance.

Application

• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) and as a component in parenteral nutrition and infusion solutions.
• Dietary Supplements & Nutraceuticals: A key ingredient in amino acid supplements, sports nutrition products, and formulations aimed at supporting mood, sleep, and cognitive function.
• Cell Culture & Fermentation Media: An essential nutrient component in microbiological media and cell culture systems for biopharmaceutical production and research.
• Biochemical Research: Employed as a standard, reagent, or substrate in enzymatic studies, metabolic pathway analysis, and protein chemistry.
• Animal Feed Additives: Incorporated into feed premixes to ensure adequate levels of this essential amino acid for livestock and poultry nutrition.
• Food Fortification: Used for the nutritional enhancement of specific food products and medical foods.

Basic Information

Product Name	L-Tryptophan Monohydrochloride
CAS No.	6159-33-7
Molecular Formula	C11H13N2O2•HCl
Molecular Weight	240.69 g/mol
Synonyms	(S)-2-Amino-3-(1H-indol-3-yl)propanoic acid hydrochloride; Tryptophan HCl; L-α-Amino-3-indolepropionic acid hydrochloride; L-Tryptophan hydrochloride; H-Trp-OH•HCl; (S)-Tryptophan hydrochloride; Tryptophan monohydrochloride
EINECS	228-208-3

Quality Control

Our L-Tryptophan Monohydrochloride is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets stringent specifications for identity, purity, and potency. Certificates of Analysis (COA) are provided with each batch, detailing key parameters such as assay, optical rotation, and impurity profiles. We can supply material compliant with various pharmacopeial standards (e.g., USP, EP) upon request, ensuring suitability for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent caking and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	98.5% ~ 101.0% (on dried basis)
Specific Rotation [α]20/D	+29.0° ~ +32.5° (c=1 in H2O)
Loss on Drying	≤ 0.5%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Chloride Content (Titration)	14.5% ~ 15.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.