Description

(R)-5-Hydroxy-2-Aminovaleric Acid is a chiral, non-proteinogenic amino acid derivative that serves as a critical building block in organic synthesis and pharmaceutical research. Its unique stereochemistry and bifunctional nature make it a valuable intermediate for constructing complex molecules with specific biological activity. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for applications ranging from peptide mimetics to active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in neurological and metabolic disorder research.
• Peptidomimetics & Conformationally Restricted Peptides: Used to introduce structural constraints and modulate the biological properties of peptide-based therapeutics.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzyme substrate investigations.
• Asymmetric Synthesis: Employed as a chiral pool starting material or auxiliary for the stereoselective construction of complex natural products and APIs.
• Ligand & Catalyst Development: Useful for creating chiral ligands for catalysis or chelating agents in metal-organic frameworks.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	(R)-5-Hydroxy-2-Aminovaleric Acid
CAS No.	6152-90-5
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	(R)-2-Amino-5-hydroxypentanoic Acid; D-5-Hydroxy-2-Aminovaleric Acid; (R)-5-Hydroxy-norvaline; (2R)-2-Amino-5-hydroxypentanoic Acid; D-2-Amino-5-hydroxypentanoic Acid; (R)-2-Amino-5-hydroxypentanoate; L-Homoserine isomer (specific); 5-Hydroxy-D-norvaline
EINECS	Contact for details

Quality Control

Our (R)-5-Hydroxy-2-Aminovaleric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.