Description

2-Chloroquinazoline is a versatile and high-value halogenated heterocyclic building block essential for advanced organic synthesis. Its primary value lies in its reactive chlorine atom, which serves as a key site for nucleophilic aromatic substitution, enabling the efficient construction of complex quinazoline derivatives. This compound is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly kinase inhibitors, anticancer agents, and other biologically active quinazoline-based compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides that utilize the quinazoline scaffold.
• Material Science Research: Serves as a building block for creating organic ligands, fluorescent dyes, and other functional organic materials.
• Academic & R&D Laboratories: Employed in methodological studies and as a standard reagent for exploring new coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	2-Chloroquinazoline
CAS No.	6141-13-5
Molecular Formula	C8H5ClN2
Molecular Weight	164.59 g/mol
Synonyms	2-Chloro-quinazoline; Quinazoline, 2-chloro-; 2-Chloroquinazoline; 2-Chloro-1,3-diazanaphthalene; NSC 51128; 2-Chlor-1,3-diazanaphthalin; 2-Cl-Quinazoline; 2-CQ
EINECS	Contact for details

Quality Control

Our 2-Chloroquinazoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.