Description

Succinylcholine Chloride Dihydrate is a neuromuscular blocking agent belonging to the class of depolarizing muscle relaxants. This compound is critical for inducing rapid muscle paralysis during surgical procedures, facilitating endotracheal intubation and mechanical ventilation. It is an essential pharmaceutical active ingredient primarily required by manufacturers of injectable anesthetic formulations and research institutions in the fields of pharmacology and anesthesiology.

Application

• Pharmaceutical Manufacturing: As the active pharmaceutical ingredient (API) in injectable neuromuscular blocking agents used in surgical anesthesia.
• Anesthesia & Surgery: For inducing short-duration muscle relaxation to facilitate tracheal intubation, endoscopic procedures, and orthopedic manipulations.
• Emergency Medicine: Used in rapid sequence intubation (RSI) protocols in emergency departments and intensive care units.
• Veterinary Medicine: Employed as a muscle relaxant in surgical procedures for animals.
• Pharmacological Research: Serves as a reference standard and tool compound in studies of neuromuscular junction physiology and drug interactions.
• Biomedical Research: Used in experimental protocols requiring temporary skeletal muscle paralysis.

Basic Information

Product Name	Succinylcholine Chloride Dihydrate
CAS No.	6101-15-1
Molecular Formula	C14H30Cl2N2O4 • 2H2O
Molecular Weight	397.31 g/mol (dihydrate)
Synonyms	Suxamethonium Chloride Dihydrate; Succinylcholine Dichloride Dihydrate; Suxamethonium Dichloride Dihydrate; Diacetylcholine Chloride Dihydrate; Anectine (brand name basis); Choline Succinate Dichloride Dihydrate; 2,2'-[(1,4-Dioxobutane-1,4-diyl)bis(oxy)]bis(N,N,N-trimethylethanaminium) Dichloride Dihydrate
EINECS	228-061-4

Quality Control

Our Succinylcholine Chloride Dihydrate is manufactured under strict quality management systems. We offer material compliant with major pharmacopoeial standards, including USP and EP monographs, ensuring it meets the stringent requirements for pharmaceutical active ingredients. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (Chloride)	Positive
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	8.0% - 10.0%
pH (Solution)	3.5 - 5.0
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.