Description

Pyrimidine, 4-Chloro-5-Fluoro-2-(Methylthio)- is a high-value halogenated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its precise molecular architecture makes it an indispensable intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of antiviral, anticancer, and other biologically active molecules containing a fluorinated pyrimidine core.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the chloro-fluoro substitution pattern enhances bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Material Science: Potential intermediate for creating specialty polymers or organic electronic materials with specific optoelectronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	Pyrimidine, 4-Chloro-5-Fluoro-2-(Methylthio)-
CAS No.	6096-45-3
Molecular Formula	C5H4ClFN2S
Molecular Weight	178.62 g/mol
Synonyms	4-Chloro-5-fluoro-2-(methylthio)pyrimidine; 2-(Methylthio)-4-chloro-5-fluoropyrimidine; 4-Chloro-5-fluoro-2-methylsulfanylpyrimidine; 5-Fluoro-4-chloro-2-(methylthio)pyrimidine; 4-Chloro-5-fluoro-2-methylmercaptopyrimidine; 6096-45-3; 4-Chloro-5-fluoro-2-(methylsulfanyl)pyrimidine
EINECS	Contact for details

Quality Control

Our Pyrimidine, 4-Chloro-5-Fluoro-2-(Methylthio)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.