Description

4-Pyrimidinol, 6-(Fluoromethyl)- (7Ci,8Ci) is a specialized fluorinated pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of a fluoromethyl group can significantly alter biological activity and metabolic stability. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial synthon in the research and development of new drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorinated pyrimidine core contributes to enhanced efficacy and environmental profile.
• Fine Chemical Building Block: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules for various industrial applications.
• Academic & Industrial Research: A valuable reagent for methodological studies in fluorination chemistry and heterocyclic compound synthesis.
• Material Science Precursor: Potential use in the synthesis of specialty chemicals for advanced materials, such as ligands for catalysts or components for electronic materials.

Basic Information

Product Name	4-Pyrimidinol, 6-(Fluoromethyl)- (7Ci,8Ci)
CAS No.	6096-25-9
Molecular Formula	C5H5FN2O
Molecular Weight	128.10 g/mol
Synonyms	6-(Fluoromethyl)pyrimidin-4-ol; 6-(Fluoromethyl)-4-pyrimidinol; 4-Hydroxy-6-(fluoromethyl)pyrimidine; 6-Fluoromethyl-4-hydroxypyrimidine; 4-Pyrimidinol, 6-(fluoromethyl)-; 6096-25-9; AI3-28445; NSC 51143
EINECS	Contact for details

Quality Control

Every batch of 4-Pyrimidinol, 6-(Fluoromethyl)- is produced under strict quality management protocols. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure compliance with exacting standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.