Description

2(1H)-Pyrimidinone, 5-Fluoro-4-Methyl- (9Ci) is a fluorinated pyrimidinone derivative, a high-value heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fluorine-substituted pyrimidine core enables precise modulation of biological activity and physicochemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate and scale new molecular entities.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and production of fluorinated drug candidates, particularly in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances bioactivity and environmental stability.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial manufacturing of complex target molecules.
• Material Science Precursor: Potential use in the synthesis of specialty polymers, ligands for catalysis, or organic electronic materials.

Basic Information

Product Name	2(1H)-Pyrimidinone, 5-Fluoro-4-Methyl- (9Ci)
CAS No.	6090-44-4
Molecular Formula	C5H5FN2O
Molecular Weight	128.10 g/mol
Synonyms	5-Fluoro-4-methylpyrimidin-2(1H)-one; 5-Fluoro-4-methyl-1H-pyrimidin-2-one; 5-Fluoro-4-methyl-2(1H)-pyrimidinone; 4-Methyl-5-fluoropyrimidin-2(1H)-one; 5-Fluoro-4-methyl-2-hydroxypyrimidine; 6090-44-4 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyrimidinone, 5-Fluoro-4-Methyl- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.