Description

L-Kynurenine Picrate Monohydrate is a high-purity, crystalline derivative of the essential amino acid metabolite L-Kynurenine, complexed with picric acid. This compound is critical for researchers and manufacturers requiring a stable, well-characterized standard for analytical and biochemical applications. It is primarily utilized in pharmaceutical research, neuroscience studies, and as a key reference material in quality control laboratories for method development and validation.

Application

• Biochemical Research Standard: Serves as a primary reference standard in studies of the kynurenine pathway, tryptophan metabolism, and related neurological processes.
• Pharmaceutical Intermediates: Used in the research and development of novel therapeutic agents targeting neurological disorders and immune modulation.
• Analytical Chemistry: Employed as a calibration standard in High-Performance Liquid Chromatography (HPLC), Liquid Chromatography-Mass Spectrometry (LC-MS), and other spectroscopic methods for accurate quantification.
• Neuroscience Studies: Applied in experimental models to investigate neuroactive properties and the role of kynurenine pathway metabolites in brain function and disease.
• Quality Control & Method Validation: Essential for validating analytical methods, ensuring accuracy, precision, and compliance in pharmaceutical and contract research organization (CRO) laboratories.

Basic Information

Product Name	L-Kynurenine Picrate Monohydrate
CAS No.	6047-19-4
Molecular Formula	C15H15N5O9 • H2O
Molecular Weight	439.32 g/mol (Monohydrate)
Synonyms	L-Kynurenine Picrate; (S)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid compound with 2,4,6-trinitrophenol monohydrate; Kynurenine picrate salt; Kynurenine trinitrophenolate; Kynurenine-2,4,6-trinitrophenol complex; Tryptophan metabolite picrate derivative
EINECS	Contact for details

Quality Control

Our L-Kynurenine Picrate Monohydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing specific results for purity, related substances, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air and moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	3.5% - 5.0% (Theoretical for monohydrate: ~4.1%)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.