Description

Taurolithocholic Acid Sodium Salt is a conjugated bile acid derivative, a key biochemical reagent and pharmaceutical intermediate. This compound is valued for its role in modulating cellular signaling pathways and its utility in advanced research. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and diagnostic sectors. Its specific properties make it a critical component for studying bile acid metabolism and related physiological processes.

Application

• Biochemical Research: Used as a standard and reagent in studies of bile acid metabolism, liver function, and cholestasis.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of more complex therapeutic agents targeting nuclear receptors like FXR (Farnesoid X Receptor).
• Cell Culture & In Vitro Studies: Employed in cell-based assays to investigate apoptosis, cell signaling, and the effects of bile acids on various cell types.
• Diagnostic Development: Potential use in the calibration and development of diagnostic kits and assays for liver and gastrointestinal disorders.
• Metabolomics & Analytical Standards: Acts as a high-purity reference standard in LC-MS, HPLC, and other analytical techniques for quantifying bile acids in biological samples.
• Enzymology Studies: Utilized as a substrate or inhibitor in enzymatic studies related to bile acid conjugation and transport.

Basic Information

Product Name	Taurolithocholic Acid Sodium Salt
CAS No.	6042-32-6
Molecular Formula	C₂₆H₄₄NNaO₅S
Molecular Weight	517.69 g/mol
Synonyms	Sodium Taurolithocholate; Taurolithocholate Sodium Salt; TLCS; 3α-Hydroxy-5β-cholan-24-oyltaurine Sodium Salt; N-(3α-Hydroxy-5β-cholan-24-oyl)-taurine Sodium Salt; Lithocholyltaurine Sodium Salt; TLC-Na; Sodium 2-[(4R)-4-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11S,11aR)-7-hydroxy-11-methyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoylamino]ethanesulfonate
EINECS	Contact for details

Quality Control

Our Taurolithocholic Acid Sodium Salt is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.