Description

L-6-Hydroxynorleucine is a non-proteinogenic amino acid derivative of significant interest in advanced biochemical synthesis. This compound serves as a crucial chiral building block and metabolic intermediate, valued for its structural role in modifying peptide properties and its utility in research. It is primarily sought by manufacturers and researchers in the pharmaceutical, biotechnology, and fine chemical sectors for applications in drug discovery, proteomics, and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediates: Key chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Modification: Used to incorporate hydroxyl functionality into synthetic peptides, altering their solubility, stability, and biological activity.
• Biochemical Research: Serves as a standard, reagent, or metabolic precursor in enzymatic studies and metabolic pathway analysis.
• Proteomics & Labeling: Potential utility in the development of affinity tags, probes, or labeled compounds for protein analysis.
• Fine Chemical Synthesis: Building block for the preparation of complex organic molecules and specialty chemicals.
• Nutritional Science Research: Investigated for its role as an analog in amino acid metabolism studies.

Basic Information

Product Name	L-6-Hydroxynorleucine
CAS No.	6033-32-5
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	(2S)-2-Amino-6-hydroxyhexanoic acid; L-2-Amino-6-hydroxycaproic acid; L-6-Hydroxynorleucine; HNL; (S)-2-Amino-6-hydroxyhexanoic acid; Norleucine, 6-hydroxy-, L-; 6-Hydroxy-L-norleucine; L-α-Amino-ε-hydroxycaproic acid
EINECS	Contact for details

Quality Control

Our L-6-Hydroxynorleucine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) with detailed HPLC, NMR, and optical rotation data are provided to guarantee consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.