Description

D-Homocystine is a high-purity, non-proteinogenic sulfur-containing amino acid derivative, specifically the D-isomer of homocystine. This compound serves as a critical chiral building block and reference standard in advanced biochemical research and pharmaceutical development. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on metabolic studies, peptide synthesis, and the investigation of sulfur amino acid pathways.

Application

• Pharmaceutical Research & Development: As a key chiral intermediate in the synthesis of novel therapeutic agents and as a reference standard for analytical method development.
• Biochemical Studies: Used in metabolic pathway research, particularly in studies related to homocysteine metabolism and associated disorders.
• Peptide Chemistry: Serves as a specialized building block for incorporating non-natural amino acid structures into synthetic peptides for structure-activity relationship (SAR) studies.
• Analytical Standard: Employed as a high-purity calibrant and reference material in chromatographic (HPLC, LC-MS) and spectroscopic analyses for accurate quantification.
• Nutritional Science Research: Investigated in studies concerning sulfur amino acid requirements, bioavailability, and metabolic interactions.

Basic Information

Product Name	D-Homocystine
CAS No.	6027-15-2
Molecular Formula	C8H16N2O4S2
Molecular Weight	268.35 g/mol
Synonyms	(R,R)-Homocystine; D-(+)-Homocystine; (2R,2'R)-3,3'-Dithiobis(2-aminobutanoic acid); (R)-3,3'-Dithiobis(2-aminobutanoic acid); D-3,3'-Dithiobis(2-aminobutanoic acid); (2R)-2-Amino-4-{[(2R)-2-amino-1-hydroxy-4-sulfanylidene-4-oxobutyl]disulfanyl}butanoic acid; D-Form Homocystine
EINECS	227-887-3

Quality Control

Our D-Homocystine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC. A Certificate of Analysis (COA) detailing specific results for identity, assay, chiral purity, and related substances is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.