Description

L-4-Hydroxyisoleucine is a non-proteinogenic amino acid derivative known for its unique biological activity. This compound is of significant interest in the nutraceutical and pharmaceutical industries due to its potential role in metabolic regulation. It is primarily sought after by manufacturers of dietary supplements, clinical nutrition products, and research institutions for applications in metabolic health and wellness.

Application

• Dietary Supplements & Nutraceuticals: A key ingredient in formulations targeting blood sugar management and metabolic syndrome support.
• Pharmaceutical Intermediates: Serves as a chiral building block for the synthesis of more complex bioactive molecules and potential drug candidates.
• Clinical Nutrition: Incorporated into specialized medical foods and enteral formulas designed for patients with metabolic disorders.
• Biochemical Research: Used as a standard or reagent in metabolic pathway studies, enzyme inhibition assays, and pharmacological research.
• Cosmeceuticals: Explored for inclusion in topical formulations aimed at improving skin health due to its potential anti-glycation properties.
• Sports Nutrition: Investigated for use in products aimed at enhancing insulin sensitivity and nutrient partitioning in athletes.

Basic Information

Product Name	L-4-Hydroxyisoleucine
CAS No.	6001-78-8
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	(2S,3R,4S)-4-Hydroxyisoleucine; L-4-Hydroxyisoleucine; 4-Hydroxy-L-isoleucine; (2S,3R,4S)-2-Amino-3-methyl-4-hydroxypentanoic acid; 4-Hydroxyisoleucine; HIL; Fenugreek amino acid extract; 4-Hydroxy-L-isoleucine from Trigonella foenum-graecum
EINECS	Contact for details

Quality Control

Our L-4-Hydroxyisoleucine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets stringent specifications for nutraceutical and research applications. Certificates of Analysis (COA) documenting identity, purity, and specific impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation and clumping.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-4-Hydroxyisoleucine)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.