Description

5-Hydroxy-Lysine is a hydroxylated derivative of the essential amino acid L-lysine, playing a crucial role in the post-translational modification of proteins. This compound is significant for its involvement in collagen cross-linking and as a key intermediate in biochemical research and synthesis. It is primarily sought after by manufacturers and researchers in the pharmaceutical, nutraceutical, and life science sectors for applications in metabolic studies, peptide synthesis, and the development of specialized biomaterials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of specialized drugs and therapeutic peptides targeting connective tissue disorders.
• Biochemical Research: Serves as a critical standard and reagent in metabolic pathway studies, particularly those involving collagen biosynthesis and lysine metabolism.
• Nutraceutical Development: Investigated as a potential ingredient in advanced dietary supplements aimed at supporting skin, bone, and joint health.
• Cosmetic Science: Applied in R&D for anti-aging and skin-repair formulations due to its role in collagen structure and stability.
• Diagnostic Reagents: Utilized in the production of assay kits and calibrators for clinical diagnostics related to amino acid metabolism.
• Academic & Industrial R&D: A fundamental building block in organic synthesis and proteomics research within university and corporate laboratories.

Basic Information

Product Name	5-Hydroxy-Lysine
CAS No.	6000-08-4
Molecular Formula	C₆H₁₄N₂O₃
Molecular Weight	162.19 g/mol
Synonyms	5-Hydroxy-L-lysine; (2S)-2,6-Diamino-5-hydroxyhexanoic acid; O5-Hydroxy-L-lysine; Hydroxylysine; 5-OH-Lys; L-5-Hydroxylysine; 2,6-Diamino-5-hydroxycaproic acid
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-Lysine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and specific tests for related substances and residual solvents. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment. We support compliance with cGMP, ISO, and other relevant regulatory frameworks for research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: +14° to +20° (c=1 in H₂O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.