Description

2,5-Difluorophenylene-1,4-Diamine, 1,4-Diamino-2,5-Difluorobenzene is a high-purity aromatic diamine building block featuring fluorine substituents on the benzene ring. This compound is critical for synthesizing advanced polymers and specialty chemicals where the introduction of fluorine atoms imparts enhanced thermal stability, chemical resistance, and unique electronic properties. It is primarily utilized by R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel monomers, ligands, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS and oncology.
• Polymer & Resin Synthesis: Serves as a monomer for producing high-performance polyimides, polyamides, and aramids with superior thermal and chemical resistance for aerospace and electronics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where fluorination improves bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated diamines used in the manufacture of liquid crystal polymers (LCPs) and organic light-emitting diode (OLED) electron transport layers.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized fluorinated dyes and pigments for high-value applications requiring color fastness and stability.
• Crosslinking Agent: Functions as a crosslinker in epoxy resin systems and other thermosetting polymers to enhance mechanical strength and glass transition temperature (Tg).

Basic Information

Product Name	2,5-Difluorophenylene-1,4-Diamine, 1,4-Diamino-2,5-Difluorobenzene
CAS No.	698-52-2
Molecular Formula	C6H6F2N2
Molecular Weight	144.12 g/mol
Synonyms	1,4-Diamino-2,5-difluorobenzene; 2,5-Difluoro-1,4-phenylenediamine; 2,5-Difluorobenzene-1,4-diamine; 2,5-Difluoro-p-phenylenediamine; 1,4-Phenylenediamine, 2,5-difluoro-; 2,5-Difluoro-1,4-diaminobenzene; 698-52-2 (CAS); p-Phenylenediamine, 2,5-difluoro-
EINECS	211-826-3

Quality Control

Our 2,5-Difluorophenylene-1,4-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents, acids, and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0% (Area %)
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.