Description

4-Pyrimidinamine, 2,5,6-Trifluoro- (9Ci) is a high-purity fluorinated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique trifluoro-substituted structure, which is essential for modulating the electronic and steric properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in oncology and antiviral research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and stability.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise fluorination patterns.

Basic Information

Product Name	4-Pyrimidinamine, 2,5,6-Trifluoro- (9Ci)
CAS No.	697-85-8
Molecular Formula	C4H2F3N3
Molecular Weight	149.07 g/mol
Synonyms	2,5,6-Trifluoropyrimidin-4-amine; 2,5,6-Trifluoro-4-pyrimidinamine; 4-Amino-2,5,6-trifluoropyrimidine; 2,5,6-Trifluoro-4-aminopyrimidine; 2,4,5-Trifluoropyrimidin-6-amine (tautomer); TFAP (abbreviation); 697-85-8 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Every batch of 4-Pyrimidinamine, 2,5,6-Trifluoro- is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.