Description

2,4-Diamino-6-Fluoropyrimidine is a high-purity fluorinated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional amino and fluoro substituents, which enable precise molecular modifications for creating complex, high-value compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral, anticancer, and antimicrobial agents, leveraging the pyrimidine core's bioactivity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluoropyrimidine structure contributes to efficacy and selectivity.
• Fine Chemical Building Block: Employed in organic synthesis for constructing complex heterocyclic compounds, dyes, and functional materials.
• Biochemical Research: Serves as a valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Nucleic Acid Chemistry: Acts as a modified nucleobase analog in the development of oligonucleotides and related probes for diagnostic applications.

Basic Information

Product Name	2,4-Diamino-6-Fluoropyrimidine
CAS No.	696-83-3
Molecular Formula	C4H5FN4
Molecular Weight	128.11 g/mol
Synonyms	6-Fluoro-2,4-pyrimidinediamine; 6-Fluoro-2,4-diaminopyrimidine; 2,4-Diamino-6-fluoropyrimidine; 6-Fluoropyrimidine-2,4-diamine; 2,4-Diamino-6-fluoro-1,3-diazine; NSC 52342; 696-83-3; 6-Fluoro-2,4-diamino-1,3-diazine
EINECS	211-800-9

Quality Control

Our 2,4-Diamino-6-Fluoropyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.