Description

Glycyl-D-Leucine is a high-purity, synthetic dipeptide composed of glycine and the D-isomer of leucine. This specific stereochemistry makes it a valuable chiral building block and reference standard for advanced research and development. It is essential for scientists and manufacturers in the pharmaceutical and biotechnology sectors who require precise, non-natural amino acid derivatives. Its primary utility lies in peptide synthesis, biochemical research, and as a critical component in the study of enzyme specificity and metabolic pathways.

Application

• Pharmaceutical Intermediate: Used as a chiral synthon in the research and development of novel therapeutic peptides and peptidomimetics.
• Biochemical Research: Serves as a standard and substrate in enzymatic studies, particularly for investigating protease specificity and inhibition.
• Peptide Synthesis: A key building block in solid-phase and solution-phase peptide synthesis for creating custom sequences with D-amino acids.
• Reference Standard: Employed in analytical laboratories for method development, calibration, and quality control of related peptide products.
• Nutritional Science Studies: Used in metabolic research to study the absorption and utilization of D-amino acid containing peptides.

Basic Information

Product Name	Glycyl-D-Leucine
CAS No.	688-13-1
Molecular Formula	C8H16N2O3
Molecular Weight	188.22 g/mol
Synonyms	Gly-D-Leu; D-Leucine, N-glycyl-; H-Gly-D-Leu-OH; N-(2-Aminoacetyl)-D-leucine; Glycyl-D-leucine; D-Leucylglycine (isomer); Glycine, N-[(1R)-1-(carboxymethyl)-3-methylbutyl]-; (R)-2-(2-Aminoacetamido)-4-methylpentanoic acid
EINECS	211-706-6

Quality Control

Our Glycyl-D-Leucine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets exacting standards for research and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.