Description

γ-Glutamylcysteine is a crucial dipeptide and the immediate biosynthetic precursor to the master antioxidant glutathione. Its significance lies in its role as a key intermediate in cellular redox regulation and detoxification pathways. This compound is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and biochemical research sectors, particularly for studying oxidative stress mechanisms and developing related therapeutic or health supplement formulations.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of Glutathione (GSH) for injectable and oral formulations.
• Nutraceutical & Dietary Supplements: Used as an active ingredient or a key component in antioxidant and liver-support supplement blends.
• Biochemical Research: Serves as a vital reagent for studying the γ-glutamyl cycle, glutathione metabolism, and cellular oxidative stress responses.
• Cell Culture & Media Supplement: Employed to enhance intracellular glutathione levels in various cell culture applications.
• Cosmeceuticals: Incorporated into advanced skincare products for its antioxidant properties and potential anti-aging benefits.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, or NMR analysis.

Basic Information

Product Name	γ-Glutamylcysteine
CAS No.	686-58-8
Molecular Formula	C8H14N2O5S
Molecular Weight	250.27 g/mol
Synonyms	γ-Glutamylcysteine; L-γ-Glutamyl-L-cysteine; (2S)-2-Amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-sulfanylethyl]carbamoyl}butanoic acid; GGC; γ-GC; Glutamylcysteine; L-Glutamyl-L-cysteine; NSC 11350
EINECS	211-690-9

Quality Control

We supply γ-Glutamylcysteine in various grades, including high-purity standards for research and pharmaceutical intermediates. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by validated methods (e.g., HPLC, NMR) are available upon request. We adhere to cGMP principles where applicable to ensure batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and easily oxidized; containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to maximize stability and shelf life.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0% - 102.0%
Optical Rotation	Specific range provided per grade
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Related Substances (HPLC)	Individual unknown ≤ 0.5%, Total ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.