Description

2-Amino-4-Hydroxypyrimidine is a versatile heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique pyrimidine core structure makes it a valuable intermediate for creating complex molecules with specific biological and chemical activities. This compound is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a building block for dyes, pigments, and complex organic ligands.
• Biochemical Research: Employed in the study of enzyme inhibitors and as a scaffold in medicinal chemistry for drug discovery.
• Material Science: Investigated for the development of organic semiconductors and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Amino-4-Hydroxypyrimidine
CAS No.	674-97-5
Molecular Formula	C4H5N3O
Molecular Weight	111.10 g/mol
Synonyms	4-Hydroxy-2-aminopyrimidine; 2-Amino-4(1H)-pyrimidinone; 2-Amino-4-pyrimidinol; 4-Hydroxy-2-pyrimidinamine; Cytosine impurity; Iso-cytosine; 4-Pyrimidinol, 2-amino-; 2-Aminopyrimidin-4-ol
EINECS	211-617-4

Quality Control

Our 2-Amino-4-Hydroxypyrimidine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with key parameters including assay, impurity profile, and residual solvents, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.