Description

H-Tyr-Gly-Oh is a high-purity dipeptide derivative, specifically the C-terminal carboxylic acid of the tyrosine-glycine sequence. This compound serves as a critical building block and intermediate in advanced organic synthesis and peptide research. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise, high-quality components for drug discovery and development.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of more complex peptides and peptidomimetics with potential therapeutic applications.
• Biochemical Research: Used as a standard or reagent in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Peptide Synthesis: A fundamental building block in solid-phase and solution-phase peptide synthesis (SPPS) for constructing custom peptide sequences.
• Chemical Biology Probes: Incorporation into probes for studying protein-protein interactions, enzyme activity, and cellular signaling pathways.
• Reference Standard: Serves as a chromatographic or spectroscopic reference standard for quality control and analytical method development.

Basic Information

Product Name	H-Tyr-Gly-Oh
CAS No.	673-08-5
Molecular Formula	C11H14N2O4
Molecular Weight	238.24 g/mol
Synonyms	L-Tyrosylglycine; Glycyl-L-tyrosine; Tyr-Gly; H-Tyr-Gly-OH; N-(2-Amino-2-oxoethyl)-L-tyrosine; L-Tyrosine, N-glycyl-; (2S)-2-[[2-Aminoacetyl]amino]-3-(4-hydroxyphenyl)propanoic acid; Tyrosine-Glycine dipeptide
EINECS	211-598-4

Quality Control

Our H-Tyr-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	-20° to -25° (c=1 in 1N HCl)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.