Description

2-(Trifluoromethyl)Pyrimidine-4,6-Diol is a high-purity fluorinated pyrimidine derivative, a key heterocyclic building block in advanced chemical synthesis. Its trifluoromethyl group and diol functionality make it a versatile intermediate for creating compounds with enhanced stability and biological activity. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethyl group.
• Material Science Research: Serves as a precursor for specialty polymers, ligands, and fluorinated organic frameworks with unique electronic properties.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Design: The diol moiety can be utilized to create chelating ligands for metal catalysis and coordination chemistry.

Basic Information

Product Name	2-(Trifluoromethyl)Pyrimidine-4,6-Diol
CAS No.	672-47-9
Molecular Formula	C5H3F3N2O2
Molecular Weight	180.09 g/mol
Synonyms	4,6-Dihydroxy-2-(trifluoromethyl)pyrimidine; 2-(Trifluoromethyl)-4,6-pyrimidinediol; 4,6-Dihydroxy-2-trifluoromethylpyrimidine; 2-Trifluoromethyl-4,6-dihydroxypyrimidine; 4,6-Pyrimidinediol, 2-(trifluoromethyl)-; NSC 403697; 4,6-Dihydroxy-2-(trifluoromethyl)-1,3-diazine
EINECS	211-590-9

Quality Control

Our 2-(Trifluoromethyl)Pyrimidine-4,6-Diol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.