Description

6-(Trifluoromethyl)Uracil is a fluorinated pyrimidine derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer drug discovery. It is primarily utilized by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the development of fluorinated nucleoside analogs and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated nucleoside analogs and other active pharmaceutical ingredients (APIs).
• Antiviral Drug Research: Used in the development of novel antiviral agents targeting viral polymerases.
• Anticancer Agent Development: Serves as a precursor in the creation of chemotherapeutic compounds that interfere with DNA/RNA synthesis.
• Agrochemical Synthesis: Employed in the research and production of advanced fluorinated pesticides and herbicides.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies involving thymidylate synthase and other pyrimidine metabolism enzymes.
• Material Science: A potential monomer or additive in the synthesis of specialty polymers with unique fluorinated properties.

Basic Information

Product Name	6-(Trifluoromethyl)Uracil
CAS No.	672-45-7
Molecular Formula	C5H3F3N2O2
Molecular Weight	180.08 g/mol
Synonyms	5-(Trifluoromethyl)uracil; 6-Trifluoromethyluracil; 2,4-Dihydroxy-5-(trifluoromethyl)pyrimidine; 5-Trifluoromethyl-2,4(1H,3H)-pyrimidinedione; 5-CF3-Uracil; 5-Trifluoromethyluracil; NSC 52355; 1H-Pyrimidine-2,4-dione, 5-(trifluoromethyl)-
EINECS	211-590-9

Quality Control

Our 6-(Trifluoromethyl)Uracil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.