Description

6-Trifluoromethyl Pyrimidin-4-Ylamine is a high-purity, versatile pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluoromethyl-substituted pyrimidine core offers significant value in modulating the physicochemical properties and biological activity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group to improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for functionalized heterocyclic compounds used in organic electronics and advanced polymer materials.
• Chemical Biology & Proteomics: Employed as a scaffold or labeling agent in the design of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	6-Trifluoromethyl Pyrimidin-4-Ylamine
CAS No.	672-41-3
Molecular Formula	C5H4F3N3
Molecular Weight	163.10 g/mol
Synonyms	4-Amino-6-(trifluoromethyl)pyrimidine; 6-(Trifluoromethyl)pyrimidin-4-amine; 4-Pyrimidinamine, 6-(trifluoromethyl)-; 6-Trifluoromethyl-4-pyrimidinamine; 4-Amino-6-trifluoromethylpyrimidine; 6-Trifluoromethyl-4-aminopyrimidine; 672-41-3; 6-Trifluoromethylpyrimidin-4-ylamine
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethyl Pyrimidin-4-Ylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.